Vitamin D 25-hydroxy
| Category | Biochemistry | ||||||
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| Test background |
25-hydroxy vitamin D3 is the storage form of vitamin D3 from which 1,25-dihydroxy vitamin D3 is synthesised. 1,25-dihydroxy vitamin D acts as a hormone and stimulates intestinal calcium/phosphate absorption and increased bone resorption. |
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| Clinical Indications |
Investigation of vitamin D deficiency 25-hydroxy vitamin D3 and 25-hydroxy vitamin D2 concentrations to assess treatment efficacy in established vitamin D deficiency Differential diagnosis of bone disease Investigations of hyperparathyroidism secondary to chronic kidney disease |
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| Reference range |
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| Sample & container required | SST (gold top) or serum (red top) | ||||||
| Sample volume | 0.5 mL | ||||||
| Transport storage | For referred samples: Stable at 2-8°C for 72 hours. Please freeze pending dispatch for analysis. Sample can be sent by first class post. |
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| Turnaround time | 1 week | ||||||
| Notes | Grossly haemolysed samples are unsuitable for this assay. |